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Recent Publications

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July 1, 2019

miRNAs Absent in Caput Sperm Are Required for Normal Embryonic Development

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January 16, 2016

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

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August 8, 2018

Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in Mice

Other Peer Reviewed Publications

Conine CC, Rando OJ. Soma-to-germline RNA communication. Nat Rev Genet. 2022 Feb;23(2):73-88. doi: 10.1038/s41576-021-00412-1. Epub 2021 Sep 20. PMID: 34545247.

 

 

 

 

 

Chan, IL, Rando, OJ, Conine, CC*. (2018). Effects of Larval Density on Gene Regulation in Caenorhabditis elegans During Routine L1 Synchronization. G3 (Bethesda), 8(5), 1787-1793. doi:10.1534/g3.118.200056. (* corresponding author)

 

Sharma, U, Sun, F, Conine, CC, Reichholf, B, Kukreja, S, Herzog, VA, Ameres, SL, Rando, OJ (2018). Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm. Dev Cell. 46, 470-480 e473 (2018).

 

 

Sharma, U, Conine, CC*, Shea, JM, Boskovic, A, Derr, AG, Bing, XY, Belleannee, C, Kucukural, A, Serra, RW, Sun, F, Song, L, Carone, BR, Ricci, EP, Li, X., Fauquier, L, Moore,M. J., Sullivan, R, Mello, CC, Garber, M, and Rando, OJ (2016). Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science 351, 391–396. (* co-first author)

 

 

Conine, CC, Moresco, JJ, Gu, W, Shirayama, M, Conte, D, Jr, Yates, JR, III, and Mello, CC. (2013). Argonautes Promote Male Fertility and Provide a Paternal Memory of Germline Gene Expression in C. elegans. Cell 155, 1532-1544.

 

 

 

Conine CC, Batista PJ, Gu W, Claycomb JM, Chavez DA, Shirayama M, Mello CC (2010). The Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. PNAS 107:3588-3593.

 

 

 

Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette- Stamm L, Yamamoto KR, Walhout AJ (2010). Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network. Mol Syst Biol. 2010 May 11;6:367.


 

 

Conine, CC, Krykbaeva, M, Song, L, Brewster, RC, Friedman, N, Rando, OJ. Flexibility and constraint in preimplantation gene regulation in mouse. bioRxiv 2020.03.13.990275 doi:

https://doi.org/10.1101/2020.03.13.990275

Pre-Prints

Patents

Conine CC, Sharma U, Rando OJ. Process of delivering small RNAs to sperm. Patent application WO2018013640A1 (publication date 10/10/2019)

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