Publications

Research Publications, peer reviewed:

Conine, CC, Sun, F, Song, L, Rivera-Pérez, JA, Rando, OJ (2019). MicroRNAs Absent in Caput Sperm Are Required for Normal Embryonic Development. Developmental cell 50, 7-8 (2019).

Conine, CC, Sun, F, Song, L, Rivera-Pérez, JA, Rando, OJ (2018). Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in Mice. Dev Cell. 46, 470-480 e473 (2018).

Sharma, U, Sun, F, Conine, CC, Reichholf, B, Kukreja, S, Herzog, VA, Ameres, SL, Rando, OJ (2018). Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm. Dev Cell. 46, 470-480 e473 (2018).

Chan, IL, Rando, OJ, Conine, CC*. (2018). Effects of Larval Density on Gene Regulation in Caenorhabditis elegans During Routine L1 Synchronization. G3 (Bethesda), 8(5), 1787-1793. doi:10.1534/g3.118.200056. (* corresponding author)

Sharma, U, Conine, CC*, Shea, JM, Boskovic, A, Derr, AG, Bing, XY, Belleannee, C, Kucukural, A, Serra, RW, Sun, F, Song, L, Carone, BR, Ricci, EP, Li, X., Fauquier, L, Moore,M. J., Sullivan, R, Mello, CC, Garber, M, and Rando, OJ (2016). Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals. Science 351, 391–396. (* co-first author)

Conine, CC, Moresco, JJ, Gu, W, Shirayama, M, Conte, D, Jr, Yates, JR, III, and Mello, CC. (2013). Argonautes Promote Male Fertility and Provide a Paternal Memory of Germline Gene Expression in C. elegans. Cell 155, 1532-1544.

Conine CC, Batista PJ, Gu W, Claycomb JM, Chavez DA, Shirayama M, Mello CC (2010). The Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans. PNAS 107:3588-3593.

Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette- Stamm L, Yamamoto KR, Walhout AJ (2010). Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network. Mol Syst Biol. 2010 May 11;6:367.

 

 

Research Publications, preprint (in review):


Conine, CC, Krykbaeva, M, Song, L, Brewster, RC, Friedman, N, Rando, OJ. Flexibility and constraint in preimplantation gene regulation in mouse. bioRxiv 2020.03.13.990275 doi: https://doi.org/10.1101/2020.03.13.990275

 

Patents:

  

Conine CC, Sharma U, Rando OJ. Process of delivering small RNAs to sperm. Patent application WO2018013640A1 (publication date 10/10/2019)